You’re invited: Next Taubman Tech Talk

February 12, 2020  //  FOUND IN: Updates & Resources

All Michigan Medicine faculty and staff are invited to the next Taubman Tech Talk, which will discuss single-cell gene expression.

The talk is entitled “United States of Single Cells,” and will be held at 5 p.m. on Thursday, Feb. 20 in the CVC’s Danto Auditorium.

It will be presented by Joshua Welch, Ph.D., an assistant professor of computational medicine and bioinformatics and computer science and engineering at U-M.

In recent years, technological developments have enabled high-throughput profiling of single-cell gene expression, epigenetic regulation, and spatial position within complex tissues, providing an opportunity to define the features that delineate cell types and states.

However, this task requires sophisticated computational methods for integrating diverse single-cell datasets from multiple experiments and biological contexts.

Welch’s talk will cover how metagene factors inferred by integrative nonnegative matrix factorization provide quantitative definition of cellular identity and its variation across biological contexts, allowing robust and scalable integration of highly heterogeneous single-cell datasets.

The lecture will be followed by a Q&A and then light refreshments.

The event is free, but registration is appreciated. Click here to register and find more information.